Detalhe da pesquisa
1.
Hypothalamic UDP Increases in Obesity and Promotes Feeding via P2Y6-Dependent Activation of AgRP Neurons.
Cell
; 162(6): 1404-17, 2015 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26359991
2.
Neonatal insulin action impairs hypothalamic neurocircuit formation in response to maternal high-fat feeding.
Cell
; 156(3): 495-509, 2014 Jan 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-24462248
3.
PDK1 deficiency in POMC-expressing cells reveals FOXO1-dependent and -independent pathways in control of energy homeostasis and stress response.
Cell Metab
; 7(4): 291-301, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18396135
4.
Hypothalamic and pituitary c-Jun N-terminal kinase 1 signaling coordinately regulates glucose metabolism.
Proc Natl Acad Sci U S A
; 107(13): 6028-33, 2010 Mar 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-20231445
5.
Integrative neurocircuits that control metabolism and food intake.
Science
; 381(6665): eabl7398, 2023 09 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37769095
6.
CerS6-dependent ceramide synthesis in hypothalamic neurons promotes ER/mitochondrial stress and impairs glucose homeostasis in obese mice.
Nat Commun
; 14(1): 7824, 2023 Nov 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38016943
7.
Arcuate Nucleus-Dependent Regulation of Metabolism-Pathways to Obesity and Diabetes Mellitus.
Endocr Rev
; 43(2): 314-328, 2022 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34490882
8.
HypoMap-a unified single-cell gene expression atlas of the murine hypothalamus.
Nat Metab
; 4(10): 1402-1419, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36266547
9.
Hypothalamic pregnenolone mediates recognition memory in the context of metabolic disorders.
Cell Metab
; 34(2): 269-284.e9, 2022 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35108514
10.
Integrative neurobiology of energy homeostasis-neurocircuits, signals and mediators.
Front Neuroendocrinol
; 31(1): 4-15, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19729032
11.
Sensing the fuels: glucose and lipid signaling in the CNS controlling energy homeostasis.
Cell Mol Life Sci
; 67(19): 3255-73, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20549539
12.
Insulin signalling in tanycytes gates hypothalamic insulin uptake and regulation of AgRP neuron activity.
Nat Metab
; 3(12): 1662-1679, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34931084
13.
Functionally distinct POMC-expressing neuron subpopulations in hypothalamus revealed by intersectional targeting.
Nat Neurosci
; 24(7): 913-929, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34002087
14.
Enhanced Stat3 activation in POMC neurons provokes negative feedback inhibition of leptin and insulin signaling in obesity.
J Neurosci
; 29(37): 11582-93, 2009 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-19759305
15.
Central insulin action in energy and glucose homeostasis.
J Clin Invest
; 116(7): 1761-6, 2006 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-16823473
16.
Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity.
J Clin Invest
; 116(7): 1886-901, 2006 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-16794735
17.
Amygdala NPY Circuits Promote the Development of Accelerated Obesity under Chronic Stress Conditions.
Cell Metab
; 30(1): 111-128.e6, 2019 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31031093
18.
Developmental programming of the hypothalamus: a matter of fat.
Nat Med
; 12(1): 52-3; discussion 53, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16397567
19.
Diet-Induced Growth Is Regulated via Acquired Leptin Resistance and Engages a Pomc-Somatostatin-Growth Hormone Circuit.
Cell Rep
; 23(6): 1728-1741, 2018 05 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29742429
20.
p53 in AgRP neurons is required for protection against diet-induced obesity via JNK1.
Nat Commun
; 9(1): 3432, 2018 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-30143607